Customer case aboutantiplatelet aggregation oxidant

antiplatelet aggregation oxidant

An investigation of the antiplatelet effects of

2018-4-5  the antiplatelet activity of succinobucol. Platelet aggregation in response to collagen and adenosine diphosphate (ADP) was studied in rabbit whole blood and platelet-rich plasma using impedance aggregometry. The effect of oxidant stress on aggregation, platelet lipid

get price

An investigation of the antiplatelet effects of

Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet-platelet and platelet-vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for

get price

An investigation of the antiplatelet effects of

Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for the antiplatelet activity of succinobucol. Platelet aggregation in response to collagen and adenosine

get price

Hydrolyzates from Pyropia columbina seaweed have

2015-12-1  Antiplatelet aggregation activity of A peptides was increased after simulated digestion process (≈157%). Peptides from both hydrolyzates were potentially bio-accessible, maintaining overall the bioactivity after gastrointestinal digestion. which would access more easily to the oxidant system and lead to high values of TEAC and DPHH

get price

Antiplatelet Agents Concise Medical Knowledge

Antiplatelet agents are medications that inhibit platelet aggregation, a critical step in the formation of the initial platelet plug. Abnormal, or inappropriate, platelet aggregation is a key step in the pathophysiology of arterial ischemic events. The primary categories of antiplatelet agents include aspirin, ADP inhibitors, phosphodiesterase

get price

(PDF) Antiplatelet aggregation and cytotoxic activity of

2015-6-10  The antiplatelet aggregation activity of the compounds was separately evaluated on collagen, adenosine diphosphate [ADP], thrombin and epinephrine

get price

Vasorelaxant and anti-platelet aggregation effects of

2009-8-17  Platelet aggregation plays a pivotal role in the progression of thromboembolic diseases pathogenesis (Cassar et al., 2003). Hence, a logical strategy to prevent or treat thrombosis and reduce the related cardiovascular disease events is to target platelet aggregation by drugs and/or dietary intervention (La Rosa et al., 1990). With this aim

get price

An investigation of the antiplatelet effects of

2016-9-29  Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet-platelet and platelet-vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for

get price

Antioxidant and Antibacterial Activities in the Leaf

2013-12-24  antiplatelet aggregation properties. Synthetic antioxidants and antimicrobials in use have been shown to have harmful side effects [3-5]; therefore, there is a need for more effective, less toxic and cost ef-fective antioxidants and antimicrobials from natural sour-

get price

An investigation of the antiplatelet effects of

Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for the antiplatelet activity of succinobucol. Platelet aggregation in response to collagen and adenosine

get price

(PDF) Antiplatelet Aggregation, Cardiotonic, Anti

Antiplatelet Aggregation, Cardiotonic, Anti-Inflammatory, Antioxidant, and Calcium Channel Antagonistic Potentials of Nepeta ruderalis Buch June 2020 BioMed Research International 2020(4):1-9

get price

Antiplatelet Aggregation Activity of Walnut Hull Extract

2017-6-1  The percentage of antiplatelet aggregation was calculated as follows: (5) APA = (A T − A C / A T) × 100 In this equation, APA is the percentage of antiplatelet aggregation, A T is the absorbance at the end of reaction for the test sample (extract- and thrombin-treated cells), and A C is the absorbance at the end of reaction for control

get price

Antiplatelet aggregation triterpene saponins from the

2015-9-1  In vitro antiplatelet aggregation activity of compounds 1–15 induced by ADP (5 μM) were test in New Zealand rabbit PRP with ozagrel as a positive control drug. 1,2,3,7,12 and 15 exhibited significant inhibitory activity of antiplatelet aggregation, and showed IC 50 values of 14.7 ± 3.7, 11.3 ± 2.5, 17.4 ± 4.6, 20.5 ± 3.1, 8.1 ±

get price

(PDF) Antiplatelet aggregation and cytotoxic activity of

2015-6-10  The antiplatelet aggregation activity of the compounds was separately evaluated on collagen, adenosine diphosphate [ADP], thrombin and epinephrine induced rat platelet aggregations.

get price

Vasorelaxant and anti-platelet aggregation effects of

2009-8-17  Platelet aggregation plays a pivotal role in the progression of thromboembolic diseases pathogenesis (Cassar et al., 2003). Hence, a logical strategy to prevent or treat thrombosis and reduce the related cardiovascular disease events is to target platelet aggregation by drugs and/or dietary intervention (La Rosa et al., 1990). With this aim

get price

(PDF) Testing antiplatelet and antioxidant activity of the

(a) Illustration of the two methods (M1 and M2) employed to measure the antiplatelet effect of A. cepa extracts; the black curve is the control, while the blue curve is the real sample (sample 6); (b) Profiles of platelet aggregation curves induced by AA, in the presence A. cepa extracts at different extract volumes (5 mL, 7.5 mL, and 20 μL A

get price

An investigation of the antiplatelet effects of

2016-9-29  Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet-platelet and platelet-vessel wall interactions, the aim of this study was to establish if antioxidant activity was responsible for the antiplatelet

get price

Antioxidant and Antibacterial Activities in the Leaf

2013-12-24  antiplatelet aggregation properties. Synthetic antioxidants and antimicrobials in use have been shown to have harmful side effects [3-5]; therefore, there is a need for more effective, less toxic and cost ef-fective antioxidants and antimicrobials from natural sour-

get price

Antiplatelet activity of flavonoid and coumarin drugs

2016-12-1  All the polyphenols tested inhibited platelet aggregation. A percentage antiplatelet activity of 88.91 ± 7.98% was recorded for naringin, 48.43 ± 8.84% for naringenin, 53.83 ± 7.87% for esculetin, 54.65 ± 6.91% for fraxetin, and 25.75 ± 4.12% for coumarin.

get price

Anti-Oxidant and Antiplatelet Properties of Maharishi

Antioxidant and Antiplatelet Properties of Maharishi Amrit Kalash [MAK-4] in Hypercholesterolemic Rabbits Publication Ninth International Symposium on Atherosclerosis, Rosemont, IL, October 6-11, 1991, p. 188 (Abstract). Authors Rao V. Panganamala, Ph.D. and Hari M. Sharma, M.D., FRCP(C). Conducted at The Ohio State Un

get price

Antiplatelet aggregation triterpene saponins from the

2015-9-1  In vitro antiplatelet aggregation activity of compounds 1–15 induced by ADP (5 μM) were test in New Zealand rabbit PRP with ozagrel as a positive control drug. 1,2,3,7,12 and 15 exhibited significant inhibitory activity of antiplatelet aggregation, and showed IC 50 values of 14.7 ± 3.7, 11.3 ± 2.5, 17.4 ± 4.6, 20.5 ± 3.1, 8.1 ±

get price

(PDF) Antiplatelet aggregation and cytotoxic activity of

2015-6-10  The antiplatelet aggregation activity of the compounds was separately evaluated on collagen, adenosine diphosphate [ADP], thrombin and epinephrine induced rat platelet aggregations.

get price

Vasorelaxant and anti-platelet aggregation effects of

2009-8-17  Platelet aggregation plays a pivotal role in the progression of thromboembolic diseases pathogenesis (Cassar et al., 2003). Hence, a logical strategy to prevent or treat thrombosis and reduce the related cardiovascular disease events is to target platelet aggregation by drugs and/or dietary intervention (La Rosa et al., 1990). With this aim

get price

Antiplatelet activity of flavonoid and coumarin drugs

2016-12-1  All the polyphenols tested inhibited platelet aggregation. A percentage antiplatelet activity of 88.91 ± 7.98% was recorded for naringin, 48.43 ± 8.84% for naringenin, 53.83 ± 7.87% for esculetin, 54.65 ± 6.91% for fraxetin, and 25.75 ± 4.12% for coumarin.

get price

Inhibition of Rat Platelet Aggregation byUrtica dioica

The strongest antiplatelet effect of OMT (50-400µg/mL) was observed on the ADP- induced aggregation with inhibitions up to 55%, while among others agonists (epinephrine, collagen, thrombin and

get price

Reveals of candidate active ingredients in Justicia and

2021-8-25  The study found the anti-thrombotic targets, clusters, biological processes, and pathways of Justicia and confirmed that the core compounds in Justicia have antiplatelet aggregation effect and can

get price

Immediate Antioxidant and Antiplatelet Effect of

statins possess a rapid antiplatelet effect, ie, within 24 hours of administration. Also of relevance is the fact that it is not fully defined whether the antiplatelet property of statins is a pleiotro-pic effect and/or is dependent on low-density lipoprotein (LDL) lowering. Addressing these issues may

get price

Antiplatelet and Antithrombotic Effects of Epimedium

2021-4-16  Background and Objective.Epimedium koreanum Nakai is a medicinal plant known for its health beneficial effects on impotence, arrhythmia, oxidation, aging, osteoporosis, and cardiovascular diseases. However, there is no report available that shows its effects on platelet functions. Here, we elucidated antiplatelet and antithrombotic effects of ethyl acetate fraction of E. koreanum.

get price

(PDF) Vitamin E potentiates the antiplatelet activity of

The antiplatelet activity of C. fragile on agonist-activated platelet aggregation, granule secretion, calcium mobilization, platelet spreading, and clot retraction was assessed.

get price

Booking Online

#